Cannabinoids as Therapeutics (Milestones in Drug Therapy) 2005th Edition by Raphael Mechoulam (PDF)

Description

Only a few years ago the endocannabinoid system was unknown. Today we are aware that endocannabinoids are involved in many of the functions of the mammalian body – in neuroprotection, appetite and suckling, pain, reproduction, anxiety, memory, bone formation etc. This volume presents an up-to-date picture of some of the major fields of endocannabinoid research. It summarizes the actions of the endocannabinoids on various physiological systems and opens new therapeutic windows to a large number of diseases.The first chapter, on the use of Cannabis in India, can be viewed as an expression of thanks to the herbal practitioners, who for centuries passed on the medical traditions associated with the drug. The chapter on chemistry is a short summary of active plant, synthetic and endogenous cannabinoids being investigated today, many of which are mentioned later in the book. Cannabidiol is an unusual cannabinoid – it does not bind to the known receptors and yet exerts a variety of effects. Hence a chapter is devoted to it. Further chapters deal with the endocannabinoid system and the endocannabinoids in a variety of conditions and physiological systems. The concluding chapter describes the research done on Sativex®, a standardized plant extract, shortly to be introduced in Canada as a drug for multiple sclerosis.The intended audience is drug researchers (medicinal chemists, pharmacologists, clinicians), neuroscientists, physiologists, and clinicians interested in the effect of the endocannabinoid system in various physiological systems.

User’s Reviews

Reviews from Amazon users which were colected at the time this book was published on the website:

⭐If you are a chemist or toxicologist this is the most thorough and comprehensive book I have read so far on the subject. It is written on a graduate school level and is not intended for the lay-man. Filled with citations to peer reviewed scientific studies and filled with detailed chemistry and molecular biology, it will take weeks to read and look up the journal articles. This is the academic level professionals in this field will love. I will value this book as a reference guild long after it has been thoroughly read and digested. I highly recommend this book for professionals in the field, physicians, pharmacologists and toxicologists. Biochemists and molecular biologists will also find it interesting, well researched, and comprehensive in scope. If you do not hold at least a B.S. in one of these subjects, you will probably not be able to understand fully what this text covers, and would be far better off with Grotenhermen and Russo’s Cannabis and Cannabinoids which is written more on an under-graduate level. Still a perfect 5 stars for professionals with a medical/biochemical background and an advanced degree. Excellent book!

⭐It is about price when world needs to know facts on canabinoids more then ever

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