From Neuron to Brain 5th Edition by John G. Nicholls (PDF)

Description

From Neuron to Brain, Fifth Edition, provides a readable, up-to-date book for use in undergraduate, graduate, and medical school courses in neuroscience. As in previous editions, the emphasis is on experiments made by electrical recordings, molecular and cellular biological techniques, andbehavioral studies on the nervous system, from simple reflexes to cognitive functions. Lines of research are followed from the inception of an idea to new findings being made in laboratories and clinics today.A major change is that this edition begins with the anatomy and physiology of the visual system, from light receptors in the retina to the perception of images. This allows the reader to appreciate right away how nerve cells act as the building blocks for perception. Detailed mechanisms of signalingare then described in later chapters. All chapters have been rewritten, and new chapters added.From Neuron to Brain will be of interest to anyone, with or without a specialized background in biological sciences, who is curious about the workings of the nervous system.RESOURCESThe From Neuron to Brain Instructor’s Resource Library includes all of the figures (including photographs) and tables from the textbook, sized and color adjusted for optimal legibility when projected.

User’s Reviews

Editorial Reviews: About the Author John G. Nicholls is Professor of Neuroscience at the International School for Advanced Studies in Trieste (known as SISSA). He was born in London in 1929 and received a medical degree from Charing Cross Hospital and a Ph.D. in physiology from the Department of Biophysics at University CollegeLondon, where he did research under the direction of Sir Bernard Katz. He has worked at University College London, at Oxford, Harvard, Yale, and Stanford Universities, and at the Biocenter in Basel. With Stephen Kuffler, he made experiments on neuroglial cells and wrote the first edition of thisbook. He is a Fellow of the Royal Society, a member of the Mexican Academy of Medicine, and the recipient of the Venezuelan Order of Andres Bello. He has given laboratory and lecture courses in neurobiology at Woods Hole and Cold Spring Harbor, and in universities in Asia, Africa, and Latin America.His work concerns regeneration of the nervous system after injury and mechanisms that give rise to the respiratory rhythm.A. Robert Martin is Professor Emeritus in the Department of Physiology at the University of Colorado School of Medicine. He was born in Saskatchewan in 1928 and majored in mathematics and physics at the University of Manitoba. He received a Ph.D. in Biophysics in 1955 from University College London,where he worked on synaptic transmission in mammalian muscle under the direction of Sir Bernard Katz. From 1955 to 1957 he did postdoctoral research in the laboratory of Herbert Jasper at the Montreal Neurological Institute, studying the behavior of single cells in the motor cortex. He has taught atMcGill University, the University of Utah, Yale University, and the University of Colorado Medical School, and has been a visiting professor at Monash University, Edinburgh University, and the Australian National University. His research has contributed to the understanding of synaptic transmission,including the mechanisms of transmitter release, electrical coupling at synapses, and properties of postsynaptic ion channels.Paul A. Fuchs is Director of Research and the John E. Bordley Professor of Otolaryngology-Head and Neck Surgery, Professor of Biomedical Engineering, Professor of Neuroscience and co-Director of the Center for Sensory Biology at the Johns Hopkins University School of Medicine. Born in St. Louis,Missouri in 1951, Fuchs graduated in biology from Reed College in 1974. He received a Ph.D. in Neuro- and Biobehavioral Sciences in 1979 from Stanford University where he investigated presynaptic inhibition at the crayfish neuromuscular junction under the direction of Donald Kennedy and PeterGetting. From 1979 to 1981 he did postdoctoral research with John Nicholls at Stanford University, examining synapse formation by leech neurons. From 1981 to 1983 he studied the efferent inhibition of auditory hair cells with Robert Fettiplace at Cambridge University. He has taught at the Universityof Colorado and the Johns Hopkins University medical schools. His research examines excitability and synaptic signaling of sensory hair cells and neurons in the vertebrate inner ear.David A. Brown is Professor of Pharmacology in the Department of Neuroscience, Physiology, and Pharmacology at University College London. He was born in London in 1936 and gained a B.Sc. in Physiology from University College London and a Ph.D. from St. Bartholomew’s Hospital Medical College(“Barts”) studying transmission in sympathetic ganglia. He then did a post-doc at the University of Chicago, where he helped design an integrated neurobiology course for graduate medical students. He has since chaired departments of Pharmacology at the School of Pharmacy and at University College inLondon, and has also worked in several labs in the United States, including the Department of Physiology and Biophysics at the University of Texas in Galveston, and as Fogarty Scholar-in-Residence at NIH in the labs of Mike Brownstein, Julie Axelrod, and Marshall Nirenberg. At Galveston, he and PaulAdams discovered the M-type potassium channel, which provided new insight into how neurotransmitters could alter nerve cell activity by regulating a voltage-gated ion channel. He continues to work on the regulation of ion channels by G protein-coupled receptors. He is a Fellow of the Royal Society,a recipient of the Feldberg Prize, and has an Honorary Doctorate from the University of Kanazawa in Japan.Mathew E. Diamond, like John Nicholls, is Professor of Cognitive Neuroscience at the International School for Advanced Studies in Trieste (SISSA). He earned a Bachelor of Science degree in Engineering from the University of Virginia in 1984 and a Ph.D. in Neurobiology from the University of NorthCarolina in 1989. Diamond was a postdoctoral fellow with Ford Ebner at Brown University and then an assistant professor at Vanderbilt University before moving to SISSA to found the Tactile Perception and Learning Laboratory in 1996. His main interest is to specify the relationship between neuronalactivity and perception. The research is carried out mostly in the tactile whisker system in rodents, but some experiments attempt to generalize the principles found in the whisker system to the processing of information in the human tactile sensory system.David A. Weisblat is Professor of Cell and Developmental Biology in the Department of Molecular and Cell Biology at the University of California, Berkeley. He was born in Kalamazoo, Michigan in 1949, studied biochemistry as an undergraduate with Bernard Babior at Harvard College, where he wasintroduced to neurobiology in a course led by John Nicholls, and received his Ph.D. from Caltech for studies on the electrophysiology of Ascaris in 1976 with Richard Russell. He began studying leech development with Gunther Stent in the Department of Molecular Biology at Berkeley and was appointedto the Zoology Department there in 1983. As a postdoc, he developed techniques for cell lineage tracing by intracellular microinjection of tracer molecules. Current research interests include the evolution of segmentation mechanisms, D quadrant specification, and axial patterning. Work from hislaboratory has helped to establish the leech Helobdella as a tractable representative of the super-phylum Lophotrochozoa, for the study of evolutionary developmental biology. He has assisted or organized courses in Africa, India, Latin America, and at Woods Hole, Massachusetts.

Reviews from Amazon users which were colected at the time this book was published on the website:

⭐When Stephen Kuffler and John Nicholls wrote the first edition of FROM NEURON TO BRAIN, published in 1976, it was a landmark text that belonged on the shelf of every neurophysiologist. It was a great piece of work – readable, elegant and relatively compact. The current edition, the 5th, is, alas, completely re-written and is a greatly expanded and far less impressive text than the first edition. Rather than concentrating most of its pages on basic neurophysiology, the 5th edition attempts to be a more general neuroscience text, covering considerably more pharmacology, systems neuroscience and behavior than the original.The inclusion of the latter is not bad, but in this edition, that lists 6 authors on the cover, I think it it is a case of “Too many cooks spoil the broth.” The organization of the chapters, particularly in the first half of the book is all over the place. Not only that, within single chapters there are far too many references, both forward and backward, to explanations in other chapters in the book. In various places, there is either too much or too little detail. Some of the figure legends will be next to impossible for anyone other than an experienced neuroscientist to understand (e.g., Fig. 14.6). One gets the feeling that there was no one person who’s job it was to read the entire book in sequence and smooth out the irregularities and contiguity problems. In general, the text has been simplified compared to the Kuffler and Nicholls original, and I cannot imagine actually following the sequence of chapters as presently organized in either a graduate or undergraduate general neuroscience course or a neurophysiology courseWhereas I use earlier editions as core readings for an advanced graduate level course called “Cellular Neurophysiology”, there is nothing in this current edition that is worth assigning instead of the chapters in the earlier editions. The book still contains a wealth of excellent information on neuroscience, but I am not sure what the target audience is. It does not contain enough specifics for a graduate level neurophysiology course. For that I would refer the reader to FOUNDATIONS OF CELLULAR NEUROPHYSIOLOGY by Johnston and Wu, and/or THE SYNAPTIC ORGANIZATION OF THE BRAIN by Shepherd and/or IONIC CHANNELS OF EXCITABLE MEMBRANES by Hille. Each of these texts differs greatly in style, but each gives the reader much more detailed information.J.M. Tepperps (11/13/14) I edited the review today, after using the text for the first semester of our year-long Foundations course required of all first year students. I added some more specific complaints and reduced my rating from 3 stars to 2 stars.

⭐This book is much more detailed than any of my courses have been so far as an undergrad. However, I bought this book rather than buying a pdf/ebook because I heard great things about it. I reference it whenever I can because of how in depth it explains it. I read the book and felt like I understood the material more than my peers in my classes because of how it explained the topics. It is one of the best neuroscience books I have come across.

⭐I think that this is a good textbook for introductory neuroscience. There are a few figures/concepts that could be better explained, but it is a far better text than the one I was assigned for my current studies.

⭐The book came in protected wrapping and it was evident that it had never been used. Thank you. My preference is that with a new course of study should came a new book. The shipping container looked like a gorilla jumped on it and threw it all over the place, but the book was in excellent condition. I will start using the book this week. Carol J Montgomery-Taylor

⭐I bought a used version of this one, cuz the original price was way too expensive and received a copy that almost resembles a new copy.

⭐This textbook does a pretty good job of explaining the material. The only downside is the strong focus on experimental data (this may be a plus or a minus depending on how you learn best!)

⭐This was required reading for my Physiological Psychology course. It provides good information, but is rather hard to read and goes very far in depth for an intro to neuro course.

⭐This is a very good book, it contains almost everything and in nutshell… tones of illustrations, graphs, pictures… answers and questions… a must have book for those who are interested in this area !!!

⭐This book continues to inspire students interested in all areas of neurobiology and neuroscience with the almost unique combination of beautiful illustrations and explanations of original experiments and clear uncluttered text.

⭐An incredibly useful textbook. I’ve lost track of the number of times I couldn’t find a decent explanation of a concept on the internet but found the perfect one in here – with diagrams!. Invaluable for my undergrad. Also smells like coffee, which I really like.

⭐I required a book on Neuroscience that would be informative and up to date. It is both and is probably the best book I have read on Neuroscience because it deals with the Brain at a cellular and molecular level; the illustrations and graphics are well laid out with concise explanations. Also, each chapter is summarised which aids learning.

⭐Excellent arrived quickly

⭐In good conditions, perfect

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