Introduction to Proteins: Structure, Function, and Motion, Second Edition (Chapman & Hall/CRC Computational Biology Series) 2nd Edition by Amit Kessel (PDF)

Description

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the structure, function, and motion of proteins for students, faculty, and researchers at all levels. The book covers proteins and enzymes across a wide range of contexts and applications, including medical disorders, drugs, toxins, chemical warfare, and animal behavior. Each chapter includes a Summary, Exercies, and References.New features in the thoroughly-updated second edition include:A brand-new chapter on enzymatic catalysis, describing enzyme biochemistry, classification, kinetics, thermodynamics, mechanisms, and applications in medicine and other industries. These are accompanied by multiple animations of biochemical reactions and mechanisms, accessible via embedded QR codes (which can be viewed by smartphones) An in-depth discussion of G-protein-coupled receptors (GPCRs)A wider-scale description of biochemical and biophysical methods for studying proteins, including fully accessible internet-based resources, such as databases and algorithmsAnimations of protein dynamics and conformational changes, accessible via embedded QR codesAdditional featuresExtensive discussion of the energetics of protein folding, stability and interactionsA comprehensive view of membrane proteins, with emphasis on structure-function relationshipCoverage of intrinsically unstructured proteins, providing a complete, realistic view of the proteome and its underlying functionsExploration of industrial applications of protein engineering and rational drug designEach chapter includes a Summary, Exercies, and ReferencesApproximately 300 color imagesDownloadable solutions manual available at www.crcpress.comFor more information, including all presentations, tables, animations, and exercises, as well as a complete teaching course on proteins’ structure and function, please visit the author’s website.. Praise for the first edition”This book captures, in a very accessible way, a growing body of literature on the structure, function and motion of proteins. This is a superb publication that would be very useful to undergraduates, graduate students, postdoctoral researchers, and instructors involved in structural biology or biophysics courses or in research on protein structure-function relationships.” –David Sheehan, ChemBioChem, 2011″Introduction to Proteins is an excellent, state-of-the-art choice for students, faculty, or researchers needing a monograph on protein structure. This is an immensely informative, thoroughly researched, up-to-date text, with broad coverage and remarkable depth. Introduction to Proteins would provide an excellent basis for an upper-level or graduate course on protein structure, and a valuable addition to the libraries of professionals interested in this centrally important field.” –Eric Martz, Biochemistry and Molecular Biology Education, 2012

User’s Reviews

Reviews from Amazon users which were colected at the time this book was published on the website:

⭐This is a great book to teach from, for university biochemistry. Lots of resources and it is extremely well written and up to date. Only thing that is unusual is the title. It is much more than an introduction to proteins, it is more of an advanced book on proteins that goes from start to advanced levels.

⭐This is the most interesting to read and complete text I have found for senior undergraduate or early graduate-level coverage of protein structure and function, and a great reference book to have on hand. I appreciate this book on so many levels! It covers:• Current computational as well as experimental methods for studying proteins, plus key databases of structural and functional information.• The theory behind our understanding of the forces and energetics underlying protein folding, stability, dynamics, ligand selectivity, and catalysis, explained in an intuitive but rigorous way.• Applications to pharmaceutical discovery and the industrial use of proteins, which are also important for those interested in careers outside academia.• All the topics in our introductory graduate course on Protein Structure, Design and Mechanism, from the determinants of structure and structure-function relationships, through kinetics and catalytic mechanisms (with the great new Chapter 9 on enzymology, which acts as a succinct text on its own), to current methods for protein structural modeling and design. In the past, we have recommended more than one text, since each one covered specific material well but was missing some other key topic. This was expensive and confusing for the students. With the 2nd edition of Kessel & Ben-Tal, the needed materials are all present in one book, whether students are new to protein structure/function or seek more depth.• The explanations are balanced by case studies that outline how these factors play out in many protein systems, including expanded coverage of G protein-coupled receptors.• A series of concept-oriented questions and problems is provided at the end of each chapter, allowing readers to assess and fill in their understanding.The color illustrations are also well designed, covering the concepts schematically along with specific examples for proteins (e.g., formation of amyloid fibrils), shown side-by-side with experimental data. While this text is significantly updated and printed in a hardcover format with easy-to-read text (larger font and pages than usual, with margins for note-taking) and comes with annotatable ebook access for free, the price is lower than several of the short paperback texts in the field. The availability of the ebook format alone for half the price will likely be attractive to students, as well as quite portable. Overall, this is a significantly enriched 2nd edition of a book we have used successfully for several years now, which I enthusiastically recommend!

⭐I used this book when studying for a course on the Mechanisms of Enzyme Catalysis. IT SAVED MY LIFE. The book made everything I was struggling with so clear! It is extremely well organized and very, very thorough which makes studying from it easy! 10/10 would recommend to anyone studying proteins and/or enzymes, or even someone who just wants to learn more. Anyone looking for a supplementary reading for your course should have this text book – even if you think you don’t need it, trust me, you do. Just one chapter of this book cleared up everything for me. I not only passed but got a great mark on the Final Exam BECAUSE OF THIS BOOK. I am so glad I have it now – I am using this book in a Proteins course I’m taking this semester as well (and based on its track record, probably for another after that)! The text was so informative, it even prompted me to take the attached photo after a successful final exam.

⭐It is really atrocious for a $130 textbook to come in black white, especially for a topic that depends as much on illustration as protein biology. What’s especially bad is that all the figures were originally in color and the legends refer to figure components by color (e.g. “red circles” and “blue circles”). So the legends are very difficult to I interpret and the figures look very bad because they have been converted to grey scale automatically without any care on how they will print.

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Keywords

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Introduction to Proteins: Structure, Function, and Motion, Second Edition (Chapman & Hall/CRC Computational Biology Series) 2nd Edition 2018 PDF Free Download
Download Introduction to Proteins: Structure, Function, and Motion, Second Edition (Chapman & Hall/CRC Computational Biology Series) 2nd Edition PDF
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